Mr. Teten Masduki began his career in the Legal Aid Agency as Head of the Labor Division. He has also worked at Indonesian Corruption Watch (ICW) and International Anti-Corruption Agencies as Secretary General of Transparency International Indonesia(2008-2012). 

In 2015, he was appointed by President Joko Widodo to serve as Presidential Chief of Staff. The Presidential Staff Office is a non-structural institution that is under and directly responsible to the President. And to assist the President and Vice President in improving the control of National Priority Programs and Strategic Issues, Mr. Teten was trusted to be the Coordinator of the Special Presidential Staff (2018). In 2019, Mr. Teten Masduki was elected to serve as Minister of Cooperatives and SMEs of the Republic of Indonesia on October 23rd, in the Cabinet "Indonesia Maju" for the 2019-2024 period which was the second period of President Joko Widodo's administration.